Boehringer Ingelheim (Canada) Ltd.

Generic Name:
tiotropium bromide monohydrate

Product Illustration Form:
dry powder inhalation device

oral inhalation

Why is it prescribed?

Spiriva® contains tiotropium bromide monohydrate.

It is used as a long-acting bronchodilator for the maintenance treatment of chronic obstructive pulmonary disease (COPD).


Side Effects

Spiriva® contains tiotropium bromide monohydrate.

Along with its needed effects, tiotropium may cause some unwanted or undesirable effects. Often, tiotropium users who use their medication properly, never experience any unwanted effects. The severity and duration of these effects are dependant on many factors including duration of therapy, dose, route of administration and individual response. Possible unwanted effects include:

  • dry mouth
  • chest pain
  • sinusitus
  • constipation
  • stomach pain

Less common:
  • allergic reactions
  • leg pain
  • tingling sensation
  • increase blood glucose
  • increase cholesterol levels

  • difficulty urinating
  • rapid heart beat

Many of these unwanted effects, especially the most common ones, may disappear with continued use. Check with the doctor or pharmacist if any of them continue or become bothersome.


Precautions and Warnings for Spiriva®

Spiriva® contains tiotropium bromide monohydrate

Tiotropium is used as a once daily maintenance bronchodilator, should not be used for the initial treatment of acute episodes of bronchospasm. It is not a rescue medication. Immediate hypersensitivity reactions (e.g. skin rash, swelling of the lip, tongue and face) may occur after administration of tiotropium. Inhaled medicines may cause inhalation-induced bronchospasm. Patients should be cautioned about getting the drug powder in their eyes. They should be advised that this may result in precipitation or worsening of narrow-angle glaucoma, eye pain or discomfort, temporary blurring of vision, visual halos or coloured images in association with red eyes from conjuntival and corneal congestion. Tiotropium should not be used more frequently than once daily. This medication should not be used in people with an allergy to tiotropium or to atropine and its derivatives (e.g. ipratropium), or to lactose. Tiotropium should be used with caution in people with narrow angle glaucoma, prostatic hyperplasia or bladder obstruction, kidney disease. Use in pregnancy: Consult your doctor or pharmacist if you suspect that you may be pregnant.
Use while breastfeeding: Consult your doctor or pharmacist before you begin breastfeeding.


Patient Information

Use Spiriva® exactly as prescribed by your doctor. It is not to be used as a rescue medication. It is to be administered once daily preferably at the same time each day by inhalation through the HandiHaler device. This medication is intended for inhalation only. Do not take by mouth. The HandiHaler device is only meant for the Spiriva®; do not use it to take any other medication. You should not inhale Spiriva® with any other device other than the HandiHaler. Become familiar with the device. Your pharmacist will show you how to use the HandiHaler. If you have any questions or concerns ask your doctor or pharmacist. You can use the HandiHaler for up to one year to take your medication before needing a replacement. Follow the manufacturer's directions for care and cleaning of the HandiHaler. It is important to clean the device once a month. Store Spiriva® and the HandiHaler in a cool dry place at room temperature (15 to 25 degrees centigrade). Protect from moisture. Do not freeze. The Spiriva® capsules should not be exposed, either in the blister pack or in the HandiHaler, to extreme temperatures. Do not expose to sunlight, heat and humidity.


Directions for Use

The recommended dosage in adults is inhalation of the contents of one capsule (18mcg) once daily.


Lung Diseases Treated with this Drug

  • bronchospasm associated with COPD
  • chronic bronchitis (COPD)
  • COPD
  • emphysema (COPD)


Need More Information?

For more information contact your physician, pharmacist, other health care professional or for general questions call your local lung association.