Medications

Apo-Cephalex tablets   

This product is manufactured by Apotex Inc. using the ingredient cephalexin.

This product is taken orally.


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orally


Why is it prescribed?

Cephalexin is used to treat infections caused by various bacteria. This material will be limited to the treatment respiratory tract infections (e.g. pneumonia, bronchitis, tonsilitis) and infections of the middle ear.


Use exactly as prescribed.
Take Apo-Cephalex tablets at even intervals around the clock as prescribed (e.g. every 6 hours translates to 4 times a day) until finished. Failure to take the complete course can result in incomplete elimination of the bacteria which can lead to a relapse of the infection. The prescribed course generally lasts a few days longer than symptoms of the infection (e.g. fever).
If you miss a dose, take it as soon as possible. If it is almost time for your next dose, do not take 2 doses at once (unless you have been instructed to do so). Contact your pharmacist if you are not sure what to do.
Apo-Cephalex tablets may produce an allergic reaction which can range in severity from a mild rash or itching to a life-threatening reaction. Contact your doctor or pharmacist if you experience rash, itching, fever, difficulty breathing, chest tightness or anything else that alarms you.  

The tablets should be stored at room temperature. Protect all forms of this medication from light and moisture, and keep it out of the reach of children.


If diarrhea occurs (severe or persistent), contact your doctor or pharmacist.


Alternatives

Other products that have the same ingredient as Apo-Cephalex tablets are •Auro-cephalexin tablet •Lupin-cephalexin suspension •PRO-Cephalexin tablets •Teva-Cephalexin capsules •Teva-Cephalexin suspension •Teva-Cephalexin tablets •

See other products used in the treatment of •pharyngitis •respiratory tract infections •sinusitis •tonsilitis •upper respiratory tract infections •

The usual adult dose for respiratory tract infections is 250 mg to 500 mg every 6 hours. The dose for children depends on their weight, and can range from 25 mg to 50 mg per kg body weight per day divided into 4 equal doses (every 6 hours).


Cephalexin is an antibiotic medication that kills various bacteria. It works by inhibiting the synthesis of one of the building blocks needed for the bacteria to make its cell wall. This results in a cell wall that is defective and more likely to rupture. The effectiveness of cephalexin depends on factors such as dose, concentration in the blood as well as other body fluids and tissue, and the susceptibility of the bacteria. Cephalexin does not kill all types of bacteria, but only those that have a sensitivity to this antibiotic. Infections caused by bacteria that are not sensitive to cephalexin will not show improvement after taking this medication.


Along with its needed effects, cephalexin may cause some unwanted or undesirable effects. Generally, cephalexin is well tolerated and many people will not experience unwanted effects. The frequency and severity of these effects is dependant on many factors including dose, duration of therapy and individual susceptibility. Possible unwanted effects include.

  • diarrhea
  • nausea

Uncommon:

  • stomach ache
  • heartburn
  • appetite loss
  • allergic reaction (hives, itching, rash, difficulty breathing)
  • headache
  • secondary fungal infection (yeast infection)

Rare:

  • sleepiness
  • fatigue
  • fever
  • itching in genital and vaginal areas

Taking the antibiotic repeatedly or for prolonged periods may result in bacterial or fungal overgrowth which can lead to a second infection. When this occurs, the cephalexin may need to be stopped and another antibiotic prescribed to treat the new infection.
Diarrhea often develops while taking cephalexin. This is sometimes caused by an overgrowth of bacteria in the gut that are not killed by the antibiotic. In severe cases, this may be life threatening and would require treatment with other antibiotics. In mild cases, symptoms disappear shortly after the drug is discontinued.
There is some evidence to show that people who are allergic to penicillin may also be allergic to cephalexin and vice versa. Be sure to inform your doctor and pharmacist of any antibiotic allergy or suspected allergy that you may have had in the past. Use is not recommended in the following situations:

  • allergy to cephalosporins (e.g. cefuroxime)

Caution is recommended in the following situations:

  • kidney disease
  • allergy to penicillin
  • stomach or intestinal disease (e.g. colitis)
  • prolonged, repeated therapy

False positive direct Coombs' tests (test used in detecting a type of blood disorder) may be caused by cephalexin.
Cephalexin may cause false urine test results for glucose.

Use in pregnancy: Generally considered safe for use if pregnant.  Consult your doctor or pharmacist if you suspect that you might be pregnant.
Use while breastfeeding: Cephalexin is excreted in breast-milk in small amounts. Generally considered safe for use if breastfeeding. Consult your pharmacist or doctor before use.


Page Last Updated: 05/10/2016